研究簡介：

從事生物計算（DNA計算和分子電路）、DNA存儲、納米孔測序、生物信息技術、納米智能機器等方面研究。近年來，以第一或通訊作者在Science Advances (2022), J. Am. Chem. Soc. (2019), Nano Letters (2016), Nucleic Acids Research (2020, 2019, 2018), Biosensors & Bioelectronics (2021),中國科學 (2015), 科學通報 (2014)等學術期刊上發表科研論文40餘篇。

作為負責人主持科研項目：國家重點研發計劃課題（2022）、國家重點研發計劃政府間重點專項（2019）、國家自然科學基金（2019，2017，2013）、北京市聯合研發大科學計劃專項（2020）、教育部裝備聯合基金（2018）、北京市自然科學基金（2018）等。參與科研項目：基金委重大應急項目（2017）、國家自然基金重點項目（2013）、國家基金委重大儀器專項（2012）等。申請發明專利7項，獲授權4項。入選2020年中國科學院創新交叉團隊。

科研/教育經曆：

2007-2010，博士，beat365

2010-2012，博士後，beat365

2013-至今，beat365任教

2014.10-2015.10，美國亞利桑那州立大學，訪問學者

2010.09-2011.11，美國普渡大學，訪問學者

代表性論文：（*通訊作者）

1.Zhang Cheng*, Xueying Ma, Xuedong Zheng, Yonggang Ke, Kuiting Chen, Dongsheng Liu, Zuhong Lu, Jing Yang, Hao Yan. Programmable Allosteric DNA Regulations for Molecular Networks and Nanomachines.Science Advances, 2022.

2.Taoli Ding, Jing Yang, Victor Pan, Zuhong Lu, Yonggang Ke,Zhang Cheng*, Shaped DNA Origami Carrier Nanopore Translocation Influenced by Aptamer based Surface Modification.Biosensors & Bioelectronics, 2021.

3.Taoli Ding, Jing Yang, Victor Pan, Nan Zhao, Zuhong Lu, Yonggang Ke andZhang Cheng*, DNA nanotechnology assisted nanopore-based analysis, Nucleic Acids Research, 2020.

4.Zhang Cheng*, Zhiyu Wang, Yan Liu, Jing Yang, Xinxin Zhang, Linqiang Pan, Yonggang Ke, Hao Yan. Nicking Assisted Reactant Recycle to Implement Entropy-Driven DNA Circuit,J. Am. Chem. Soc., 2019.

5.Xuedong Zheng, Jing Yang, Changjun Zhou,Zhang Cheng*, Qiang Zhang, Xiaopeng Wei, Allosteric DNAzyme-based DNA logic circuit: operations and dynamic analysis,Nucleic Acids Research, 2019.

6.Yang Jing, Wu, Ranfeng, Wang Zhiyu, Pan Linqiang, Zhang Qiang, Lu Zuhong,Zhang Cheng*, Entropy-Driven DNA Logic Circuits Regulated by DNAzyme,Nucleic Acids Research, 2018.

7.Cheng Zhang*, Jing Yang, Shuoxing Jiang, Yan Liu and Hao Yan, DNAzyme-Based Logic Gate-Mediated DNA Self-Assembly.Nano Letters, 2016.

8.Jing Yang, Shuoxing Jiang, Xiangrong Liu, Linqiang Pan,Cheng Zhang*, Aptamer-Binding Directed DNA Origami Pattern for Logic Gates,ACS Appl. Mater. Interfaces, 2016.

9.Yafei Dong, Chen dong, Fei Wan, Jing Yang andCheng Zhang*, Development of DNA computing and information processing based on DNA-strand displacement,中國科學, 2015.

10.Jing Yang, Jingjing Ma, Shi Liu,Zhang Cheng*, A molecular cryptography model based on structures of DNA self-assembly,科學通報, 2014.